Kirk Lab Publications
Rath, P., Shi, H., Maruniak, J., Litofsky, NS, Maria, B and Kirk, MD. (2008) Stem Cells as Vectors to Deliver HSV/tK Gene Therapy for Malignant Gliomas. Current Stem Cell Research and Therapy. Manuscript in Preparation.
Pierret, C., Morrison, J.A. and Kirk, M.D. (2008) Treatment of Lysosomal Storage Disorders: Focus on the Neuronal Ceroid-Lipofuscinoses. Acta Neurobiologiae Experimentalis. 68(3). In Press.
Pierret, C., Spears, K., Morrison, J.A., Maruniak, J.A., Katz, M.L. and Kirk, M.D. (2007) Embryonic stem cell-derived cultures exhibiting elements of a neural stem cell niche. Stem Cells Dev. 16(6):1017-26.
Lei B, Tullis GE, Kirk MD, Zhang K and Katz ML. (2006) Ocular phenotype in a mouse gene knockout model for infantile neuronal ceroid lipofuscinosis. J Neurosci Res. 2006 Oct;84(5):1139-49.
Pierret, C., Spears, K., Maruniak, J. and Kirk, M.D. (2006) Neural Crest as the Source of Adult Stem Cells. Stem Cells & Development. 2006 Apr;15(2):286-91.
Serfozo, P., Schlarman, M., Pierret, C., Maria, B. and Kirk, M.D. (2006) Selective migration of neuralized embryonic stem cells to stem cell factor and media conditioned by glioma cell lines. Cancer Cell International. 6:1 doi:10.1186/1475-2867-6-1.
Meyer, J.S., Katz, M.L., Maruniak, J.A. and Kirk, M.D. (2006) Embryonic stem cell-derived neural precursors incorporate into the degenerating retina and enhance survival of host photoreceptors . Stem Cells. 2006 Feb;24(2):274-83. Epub 2005 Aug 25.
Meyer, J.S., Katz, M.L. and Kirk, M.D. (2005) Stem Cells For Retinal Degenerative Disorders. Annals of the New York Academy of Sciences. 1049: 135-145 .
Meyer JS, Katz ML, Maruniak JA and Kirk MD. (2004) Neural differentiation of mouse embryonic stem cells in vitro and after transplantation into the eyes of mice with hereditary retinal degeneration. Brain Research. 1014(1): 131-144.
Vanmali BH, Romanova E, Messner MC, Singh M, Maruniak J, Sweedler J and Kirk MD. (2003) Enhanced growth by bag cell neurons of Aplysia in response to endogenous neurotrophic factors. J Neurobiol. 56(1):78-93.
Sánchez, J.A.D. and Kirk, M.D. (2002) Ingestion motor programs of Aplysia are modulated by short-term synaptic enhancement in cerebral-buccal interneuron pathways. Invert Neurosci., 4(4): 199-212.
Montgomery, M., Messner, M.C. and Kirk, M.D. (2002) Arterial cells and CNS sheath cells from Aplysia californica produce factors that enhance neurite outgrowth in co-cultured neurons. Invert Neurosci., 4(3): 141-155.
Sanchez JA and Kirk MD. (2001) Cerebral-buccal pathways in Aplysia californica: synaptic connections, cooperative interneuronal effects and feedback during buccal motor programs. J Comp Physiol., 187:801-815.
Kirk MD, Meyer JS, Miller MW and Govind CK. (2001) Dichotomy in phasic-tonic neuromuscular structure of crayfish inhibitory axons. J. Comp. Neurol.,435(3):283-90.
Sanchez JA, Li Y and Kirk MD. (2000) Regeneration of cerebral-buccal interneurons and recovery of ingestion buccal motor programs in Aplysia after CNS lesions. J. Neurophysiol. 84(6):2961-74.
Sanchez JA and Kirk MD. (2000) Short-Term Synaptic Enhancement Modulates Ingestion Motor Programs of Aplysia. J. Neurosci. 20(14):RC85.
Johnson SL, Schroeder ML, Sanchez JA and Kirk MD. (1999) Axonal regeneration in the central nervous system of Aplysia californica determined by anterograde transport of biocytin. J. Comp. Neurol. 406(4):476-86.
Scott ML, Danzer SC, Govind CK and Kirk MD. (1997) Morphological correlates of neural regeneration in the feeding system of Aplysia californica after central nervous system lesions. J. Comp. Neurol. 387(2):279-90.
Ting, A.E., Hazuka, C.D., Hsu, S., Kirk, M.D., Bean, A.J. and Scheller, R.H. (1995) rsec6 and rsec8, mammalian homologs of yeast proteins essential for secretion. Proc. Natl. Acad. Sci. 92: 9613-9617.
Scott ML, Li Y and Kirk MD. (1995) Functional neural regeneration in the feeding system of Aplysia: behavioral recovery correlated with changes in buccal motor output. J. Neurophysiol. 73(1):39-55.
Lee, M.T., Glidden, R. Young, S.M., Jackson, D.A. and Kirk, M.D. (1995) Pathways mediating abdominal phasic flexor muscle activity in crayfish with chronically cut nerve cords. J. Comp. Physiology. 176: 91-102.
Ross TL, Govind CK and Kirk MD. (1994) Neuromuscular regeneration by buccal motoneuron B15 after peripheral nerve crush in Aplysia californica. J. Neurophysiol. 72(4):1897-910.
Katz PS, Kirk MD and Govind CK. (1993) Facilitation and depression at different branches of the same motor axon: evidence for presynaptic differences in release. J. Neurosci. 13(7):3075-89.
Jordan, R., Cohen, K.P. and Kirk, M.D. (1993) Control of intrinsic buccal muscles by motoneurons B11, B15, and B16 in Aplysia californica. J. Exp. Zool. 265: 496-506.
Scott, M.L. and Kirk, M.D. (1992) Recovery of consummatory feeding after bilateral lesions to the cerebral-buccal connectives in Aplysia californica. Brain Res. 585: 272-274.
Govind, C.K., Blundon, J. and Kirk, M.D. (1992) Functional degeneration of central stumps of transected sensory axons in the crayfish. J. Comp. Neurol. 322: 111-120.
Kirk, M.D. and Govind, C.K. (1992) Early innervation of abdominal swimmeret muscles in developing lobsters. J. Exp. Zool. 261: 298-309.
Kirk, M.D., McClellan, A. and Harrelson, A. (1992) Molecular and Cellular Events in Neural Development and Regeneration. J. Exp. Zool. 261(3): 233.
Nambu, J. and Kirk, M.D. (1992) Molecular biology and function of neuropeptides in Aplysia, in Techniques for the Genetic Analysis of Brain and Behavior: Focus on the Mouse , D. Goldowitz, D. Wahlsten, and R. Wimer, Eds., Elsevier Press, New York.
Scott, M.L., Govind, C.K. and Kirk, M.D. (1991) Neuromuscular organization of the buccal system in Aplysia californica. J. Comp. Neurol. 312(2): 207-222.
Church, P.J., Cohen, K.P., Scott, M.L. and Kirk, M.D. (1991) Peptidergic motoneurons in the buccal ganglia of Aplysia californica: Immunocytochemical, morphological, and physiological characterizations. J. Comp. Physiol. 168(3): 323-350.
Kirk, M.D. and Govind, C.K. (1990) Presynaptic inhibition of primary afferent synapses in the crayfish, In Frontiers in Crustacean Neurobiology, Ed. by K. Wiese, W.-D. Krenz, J. Tautz, H. Reichert, B. Mulloney, Birkhauser Verlag, Berlin, pp. 140-151.
Plummer, M.R. and Kirk, M.D. (1990) Premotor neurons B51 and B52 in the buccal ganglia of Aplysia californica: Synaptic connections, effects on ongoing rhythms, and peptide modulation. J. Neurophysiol. 63(3): 539-558.
Kirk, M.D. (1989) Premotor neurons in the feeding system of Aplysia. J. Neurobiol. 20(5): 497-512.
Rathouz, M.M. and Kirk, M.D. (1988) Localization of catecholamines in the buccal ganglia of Aplysia californica. Brain Res. 458(1): 170-175.
Govind, C.K., Kirk, M.D. and Pearce, J. (1988) Highly active neuromuscular system in developing lobsters with programmed obsolescence. J. Comp. Neurol. 272(3): 437-449.
Kirk, M.D., Taussig, R. and Scheller, R.H. (1988) Egg-laying hormone, serotonin, and cyclic nucleotide modulation of ionic currents in the identified motoneuron B16 of Aplysia. J. Neurosci. 8(4): 1181-1193.
Kreiner, T., Kirk, M.D. and Scheller, R.H. (1987) Cellular and synaptic morphology of a feeding motor circuit in Aplysia californica. J. Comp. Neurol. 264(3): 311-325.
Sossin, W.S., Kirk, M.D. and Scheller, R.H. (1987) Peptidergic modulation of neuronal circuitry controlling feeding in Aplysia. J. Neurosci. 7(3): 671-681.
Scheller, R.H. and Kirk, M.D. (1987) Neuropeptides in identified Aplysia neurons: precursor structure, biosynthesis and physiological actions. Trends Neurosci. 10(1): 432-438.
Kirk, M.D. and Scheller, R.H. (1986) Egg-laying hormone of Aplysia induces a voltage-dependent slow inward current carried by Na+ in an identified motoneuron. Proc. Natl. Acad. Sci. 83(9): 3017-3021.
Kirk, M.D., Dumont, J.P.C. and Wine, J.J. (1986) Local inhibitor of the crayfish telson-flexor motor giant neurons: morphology and physiology. J. Comp. Physiol. 158(1): 69-79.
Kirk, M.D. (1985) Presynaptic inhibition in the crayfish CNS: pathways and synaptic mechanisms. J. Neurophysiol. 54(5): 1305-1325.
Kirk, M.D. and Wine, J.J. (1984) Identified interneurons produce both primary afferent depolarization and presynaptic inhibition. Science. 225(4664): 854-856.
Kirk, M.D., Prugh, J.I. and Glantz, R.M. (1983) Retinal illumination produces synaptic inhibition of a neurosecretory organ in the crayfish, Pacifastacus leniusculus (Dana) J. Neurobiol. 14(6): 473-480.
Kirk, M.D. and Govind, C.K. (1983) Innervation and motor patterns of the abdominal superficial flexor muscles in larval lobsters. J. Neurobiol. 14(5): 399-405.
Kirk, M.D., Waldrop, B. and Glantz, R.M. (1983) A quantitative correlation of contour sensitivity and dendritic density in the crayfish visual system. Brain Res. 274(2): 231-237.
Glantz, R.M., Kirk, M.D. and Arechiga, H. (1983) Light input to crustacean neurosecretory cells. Brain Res. 265(2): 307-311.
Kirk, M.D., Waldrop, B. and Glantz, R.M. (1983) The crayfish sustaining fibers. II. Responses to illumination, membrane properties and adaptation. J. Comp. Physiol. 150: 419-425.
Kirk, M.D., Waldrop, B. and Glantz, R.M. (1982) The crayfish sustaining fibers. I. Morphological representation of visual space in the second optic neuropil. J. Comp. Physiol. 146: 175-179.
Glantz, R.M., Kirk, M.D. and Viancour, T. (1981) Interneurons of the crayfish: the relationship between dendrite location and afferent input. J. Neurobiol. 12(4): 311-328.
Kirk, M.D. and Glantz, R.M. (1981) Impulse pattern generation in a crayfish abdominal postural motoneuron. J. Comp. Physiol. 141: 183-196.
Glantz, R.M. and Kirk, M.D. (1980) Intercellular dye migration and electrotonic coupling within neuronal networks of the crayfish brain. J. Comp. Physiol. 140: 121-133.